Introduction
Feline Leukemia Virus (FeLV) is a typical C-type oncovirus. It is the main cause of death among cats. It mainly affects cats under 5 years old and overcrowded. It spreads through licking, biting and ingestion of excretions and secretions. A 27 kilodalton protein moiety, p27, is a structural component of the inner viral core and is the major FeLV group-specific antigen. It can be found in great abundance in the cytoplasm of infected leukocytes and platelets and in soluble form in the plasma and serum of viremic cats. Positive detection of protein p27, the positive result, implicates that at least infected blood cells have shed the FeLV p27 in the circulating blood fraction.
Feline Immunodeficiency Virus (FIV) develops a slow infection, characterized by mainly affecting lymphocytes and macrophages, particularly CD4-marked lymphocytes, resembling the human immunodeficiency virus. It usually appears after 5 years of age due to its prolonged incubation period. It can also be transmitted through close and prolonged contact and by transplacental infection and through colostrum. Once the individual is infected it remains as a carrier for life. FIV is isolated in saliva, blood, tears and cerebrospinal fluid. From the infected cats two thirds do not develop the disease cause by this virus (unlike the HIV), in the remaining third the virus modifies the immune response, causing the immunodeficiency that eventually leads to secondary infections that may cause animal death.
Principles
The test-it FeLV/FIV CAT is designed for the simultaneous detection of FeLV p27 antigens and anti-FIV antibodies in feline whole blood, serum or plasma. The test results can appear on Control lines (C) and Test lines (T) by means of the principles of immunochromatography.
Characteristics
- rapid test of detection of FeLV antigens and FIV antibodies.
- results between 5 ~ 10 minutes.
- expensive equipment not required.
- easy storage.
- simple in use.
- high-purity and high-quality materials of the diagnostic kit increases its sensitivity and specificity.
Contents
5 or 10 tests, including test device, diluent (buffer) and disposable dropper.